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Nucleofill Medium 1.5ml

Nucleofill Medium is an innovation in aesthetics and antiaging. A biostimulator for deep skin renewal and bioreconstruction with a three-way mechanism.
This innovative treatment works on three levels:

  • Lifts
  • Antioxidant effect
  • Moisturizing
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69,90 Excl. VAT

Nucleofill Medium provides a significant and lasting rejuvenating effect.

Nucleofill is an innovation in aesthetic and anti-aging medicine due to its polynucleotide-based skin biostimulation technology. The polynucleotides found in Nucleofill Medium stimulate cell renewal in an effective, long-lasting and preventive way.

1- Receptors on fibroblasts
The receptors are stimulated and convert the fibroblasts into myofibroblasts. The production of type 1 collagen and elastin is stimulated, resulting in plumper and more toned skin.

2- Captures free radicals
Nucleofill Medium provides a powerful antioxidant effect.

3- Binds to water molecules
The polynucleotides bind to water and provide long-term isosmotic hydration of the extracellular matrix. The skin receives deep hydration and increases firmness.


Nucleofill is intended for everyone, regardless of age , who:
- want a visible rejuvenating effect without disturbing the facial features
- want to reduce the visibility of wrinkles, lines and increase firmness
- for people who want to prevent aging
- for people exposed to oxidative stress (through air pollution, sun exposure, smoking, poor diet, etc.)
- have loose and dehydrated skin
- before filler treatments to extend the aesthetic duration

- Nucleofill does not contain sugar or proteins, which minimizes the risk of allergies.
- Nucleofill is available in two strengths (Medium 20 mg/ml and Strong 25 mg/ml), the choice depends on the condition of the skin and not on age.

The manufacturer, PromoItalia, recommends three different treatment techniques:

1. The 5-point technique using a needle

2. Retrograde linear technique using a cannula

3. Multi-injection technique using one needle

PromoItalia recommends 4 treatments every 15-30 days.

Additional information

Weight 0,070 kg
Dimensions 19,5 × 9 × 4,5 cm

Field of application

Skin exposed to oxidative stress, lack of oxygen
Dehydrated skin


Gel with 2% polynucleotides
pH between 6.8-7.2
Viscosity 28-43 PA *
1 x 1.5 ml pre-filled syringe
2 x 30G 13mm

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